Course Content


2 - Guassian is the key



Stable analytical systems will produce the same Gaussian distribution of data.  When a system undergoes a change, an unexpected data point will be produced.  In this activity, participants will demonstrate the foundational principles of statistical QC (SQC).

Key Message

  • The accuracy and precision of an analytical system describes WHERE WE ARE.
  • The basis of SQC is knowing WHERE WE ARE and WHERE WE EXPECT TO BE.
  • If WHERE WE ARE with our current observed value is not WHERE WE EXPECT TO BE, then a change has occurred.

Self Assessment

Can you: 

  • List the performance specifications that describe WHERE WE ARE with an analytical system?
  • Define SQC and how it applies to monitoring their analytical system?
  • Define the criteria required for SQC to monitor change?